Posted by: Sabio Lantz | August 29, 2009

Wheat & Grains

Type 1 Diabetes Linked To Immune Response To Wheat. (Aug. 2009, Diabetes).

Peter at Hyperlipid: Pullulanse causes arthritis

There is a fairly innocent little bug called klebsiella pneumoniae which lives not only in the soil but in the intestine of many of us, probably most of us. It is a niche bacterium which exploits a particular food source. It eats starch, but not just any starch. Starch is made of long chains of glucose. The chains are branched. At the branch points there are triplets of glucose which will not fit in to the normal digestive machinery possessed by human beings, so they get left undigested. Klebsiella eats these triplets of glucose. It has a special enzyme, pullulanase, to break them down. Happy bacterium.

Unfortumately there is a large subgroup of the population who’s immune system “sees” pullulanase as something to attack. These people have a special marker on their white blood cells called HLA B27. They attack pullulanase as if it were an invading nasty. It is unfortunate that the structure of pullulanase and the structure of the collagen which forms our joints is similar. An attack on pullulanase results in collateral damage to the collagen of our ligaments and joints, most particularly those of our spine.

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